In the Erasmus MC Liver Center large liver tumors can be treated with a combination of closing off the feeding blood vessel (embolization), combined with leaving high-dose chemotherapy in the tumor. This technique is called chemo embolization and is performed percutaneously (=through the skin). From the groin or wrist, the interventional radiologist of the Liver Center advances a vascular catheter through the arterial system to just in front of the liver tumor. After checking the correct position of the vascular catheter, chemotherapy balls are injected into the tumor, after which this blood vessel is glued shut. This causes the tumor to shrivel over time. Often several times are needed to adequately treat a tumor. The treatment can also take place as a bridge to a liver transplant.